Pacijente treba pažljivo pratiti u cilju prepoznavanja znakova i simptoma respiratorne depresije i sedacije. U ovom pogledu se preporučuje informisanje pacijenata i njihovih staratelja (kada je to primenljivo) o značajnosti prepoznavanja ovih simptoma (videti odeljak 4.5).
Ukoliko ste trudni ili dojite, mislite da ste trudni ili planirate trudnoću, obratite se Vašem lekaru ili farmaceutu za savet pre nego što uzmete ovaj lek.
Tramadol is often a nontraditional centrally performing analgesic using a dual mechanism of motion. This is a weak opioid as well as a reuptake inhibitor for serotonin and norepinephrine.
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Check with the health care provider regarding what option may be chosen as an alternative to using this medicine in case of susceptible circumstances. Adhere to the dose very carefully. If utilized the drugs more than proposed, odds are that you can create tolerance to the drug.
Hronična upotreba (čak i terapijskih doza) može dovesti do razvoja fizičke i psihičke zavisnosti: prekid terapije može dovesti do pojave rebound fenomena ili fenomena obustave (videti odeljak 4.4). Prijavljena je i zloupotreba benzodiazepina.
Using this drugs with any of the next medicines is normally not proposed, but could be demanded in some cases. If both of those medicines are prescribed collectively, your health care provider might change the dose or how frequently you use one particular or equally in the medicines.
imate nasledni poremećaj koji se karakteriše stvaranjem plikova po koži, bolovima u stomaku i poremećajima mozga i nervnog sistema (porfirija).
This medication should really come with a Medication Manual. Read through and Adhere to the Directions very click here carefully. Read it again each time you refill your prescription in case There may be new data. Inquire your health care provider When you have any inquiries.
Codeine is modified into a solid opioid drug (morphine) in The body. In many people, this alteration takes place speedier plus more totally than normal, which boosts the danger of quite severe side effects.
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Tramadol and acetaminophen mix is utilized to relieve acute soreness critical more than enough to require an opioid therapy and when other agony medicines did not operate properly plenty of or can't be tolerated.